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PDBsum entry 4b6d
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protein ligands metals Protein-protein interface(s) links
Signaling protein PDB id
4b6d

 

 

 

 

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Contents
Protein chains
60 a.a.
57 a.a.
Ligands
GOL
Metals
_ZN ×12
Waters ×163
PDB id:
4b6d
Name: Signaling protein
Title: Structure of the atypical c1 domain of mgcracgap
Structure: Rac gtpase-activating protein 1. Chain: a, b, c, d, e, f. Fragment: c1 domain, residues 284-339. Synonym: male germ cell racgap, mgcracgap, protein cyk4 homolg, cyk4, hscyk-4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codon plus ril.
Resolution:
2.20Å     R-factor:   0.213     R-free:   0.236
Authors: V.E.Pye,S.Lekomtsev,M.Petronczki,P.Cherepanov
Key ref: S.Lekomtsev et al. (2012). Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis. Nature, 492, 276-279. PubMed id: 23235882
Date:
09-Aug-12     Release date:   12-Dec-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9H0H5  (RGAP1_HUMAN) -  Rac GTPase-activating protein 1 from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		632 a.a.
60 a.a.*
Protein chains
Pfam   ArchSchema ?
Q9H0H5  (RGAP1_HUMAN) -  Rac GTPase-activating protein 1 from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		632 a.a.
57 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 5 residue positions (black crosses)

 

 
Nature 492:276-279 (2012)
PubMed id: 23235882  
 
 
Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis.
S.Lekomtsev, K.C.Su, V.E.Pye, K.Blight, S.Sundaramoorthy, T.Takaki, L.M.Collinson, P.Cherepanov, N.Divecha, M.Petronczki.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23325360 K.Baumann (2013).
Cell cycle: Centralspindlin - the missing link.
  Nat Rev Mol Cell Biol, 14, 68.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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