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PDBsum entry 4ac4

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protein ligands Protein-protein interface(s) links
Transport protein PDB id
4ac4

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
116 a.a.
Ligands
HKA ×2
Waters ×133
PDB id:
4ac4
Name: Transport protein
Title: Crystal structure of transthyretin in complex with ligand c-18
Structure: Transthyretin. Chain: a, b. Synonym: attr, prealbumin, tbpa. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.80Å     R-factor:   0.222     R-free:   0.258
Authors: D.Tomar,T.Khan,R.R.Singh,S.Mishra,S.Gupta,A.Surolia,D.M.Salunke
Key ref: D.Tomar et al. (2012). Crystallographic study of novel transthyretin ligands exhibiting negative-cooperativity between two thyroxine binding sites. Plos One, 7, e43522. PubMed id: 22973437
Date:
13-Dec-11     Release date:   26-Dec-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P02766  (TTHY_HUMAN) -  Transthyretin from Homo sapiens
Seq:
Struc:
147 a.a.
116 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
Plos One 7:e43522 (2012)
PubMed id: 22973437  
 
 
Crystallographic study of novel transthyretin ligands exhibiting negative-cooperativity between two thyroxine binding sites.
D.Tomar, T.Khan, R.R.Singh, S.Mishra, S.Gupta, A.Surolia, D.M.Salunke.
 
  ABSTRACT  
 
No abstract given.

 

 

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