PDBsum entry 4abk

Transferase

PDB id: 4abk

Contents

Protein chain

182 a.a.

Ligands

AR6

Waters ×135

PDB id:

4abk

Name:

Transferase

Title:

Human parp14 (artd8, bal2) - macro domain 3 in complex with adenosine- 5-diphosphoribose

Structure:

Poly [adp-ribose] polymerase 14. Chain: a. Fragment: macro domain 3, residues 1208-1388. Synonym: adp-ribose transferase, parp-14, b aggressive lymphoma protein 2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3 prare.

Resolution:

1.60Å R-factor: 0.168 R-free: 0.206

Authors:

T.Karlberg,M.Moche,A.G.Thorsell,C.H.Arrowsmith,C.Bountra,A.M.Edwards, T.Ekblad,J.Weigelt,H.Schuler

Key ref:

A.H.Forst et al. (2013). Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains. Structure, 21, 462-475. PubMed id: 23473667 DOI: 10.1016/j.str.2012.12.019

Date:

08-Dec-11 Release date: 19-Dec-12

Protein chain

Q460N5  (PAR14_HUMAN) -  Protein mono-ADP-ribosyltransferase PARP14 from Homo sapiens

Seq: 1801 a.a.

Struc: 182 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.4.2.- - ?????

DOI no: 10.1016/j.str.2012.12.019

Structure 21:462-475 (2013)

PubMed id: 23473667

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.

A.H.Forst, T.Karlberg, N.Herzog, A.G.Thorsell, A.Gross, K.L.Feijs, P.Verheugd, P.Kursula, B.Nijmeijer, E.Kremmer, H.Kleine, A.G.Ladurner, H.Schüler, B.Lüscher.

ABSTRACT

No abstract given.