PDBsum entry 4a8h

Transferase

PDB id: 4a8h

Contents

Protein chains

341 a.a.

Ligands

PUW ×2

TRS ×2

SO4 ×2

EDO ×3

Metals

_NI ×2

Waters ×284

PDB id:

4a8h

Name:

Transferase

Title:

Crystal structure of putrescine transcarbamylase from enterococcus faecalis with n-(phosphonoacetyl)-putrescine

Structure:

Putrescine carbamoyltransferase. Chain: a, b. Synonym: ptc, ptcase, agmatine catabolism protein b, putrescine transcarbamoylase, putrescine transcarbamylase. Engineered: yes

Source:

Enterococcus faecalis. Organism_taxid: 1351. Strain: sd10. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.50Å R-factor: 0.184 R-free: 0.217

Authors:

L.M.Polo,F.Gil-Ortiz,V.Rubio

Key ref:

L.M.Polo et al. (2012). New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine. Plos One, 7, e31528. PubMed id: 22363663

Date:

21-Nov-11 Release date: 15-Feb-12

Protein chains

Q837U7  (PTC_ENTFA) -  Putrescine carbamoyltransferase from Enterococcus faecalis (strain ATCC 700802 / V583)

Seq: 339 a.a.

Struc: 341 a.a.

Enzyme reactions

• Enzyme class: E.C.2.1.3.6 - putrescine carbamoyltransferase.
• Reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + phosphate + H⁺

carbamoyl phosphate + putrescine = N-carbamoylputrescine + phosphate (Bound ligand (Het Group name = PUW) matches with 57.14% similarity) + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Plos One 7:e31528 (2012)

PubMed id: 22363663

New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.

L.M.Polo, F.Gil-Ortiz, A.Cantín, V.Rubio.

ABSTRACT

No abstract given.