PDBsum entry 4a2m

Transcription

PDB id: 4a2m

Contents

Protein chains

741 a.a.

Ligands

NGS-GCD ×4

PDB id:

4a2m

Name:

Transcription

Title:

Structure of the periplasmic domain of the heparin and heparan sulphate sensing hybrid two component system bt4663 in apo and ligand bound forms

Structure:

Two-component system sensor histidine kinase/response. Chain: a, b, c, d. Fragment: periplasmic domain, residues 1-787. Synonym: bt_4663. Engineered: yes

Source:

Bacteroides thetaiotaomicron. Organism_taxid: 226186. Strain: vpi-5482. Atcc: 29148. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

3.40Å R-factor: 0.269 R-free: 0.286

Authors:

E.C.Lowe,A.Basle,M.Czjzek,S.J.Firbank,D.N.Bolam

Key ref:

E.C.Lowe et al. (2012). A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system. Proc Natl Acad Sci U S A, 109, 7298-7303. PubMed id: 22532667

Date:

27-Sep-11 Release date: 02-May-12

Protein chains

Q89YR8  (Q89YR8_BACTN) -  histidine kinase from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)

Seq: 1353 a.a.

Struc: 741 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.13.3 - histidine kinase.
• Reaction: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Proc Natl Acad Sci U S A 109:7298-7303 (2012)

PubMed id: 22532667

A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system.

E.C.Lowe, A.Baslé, M.Czjzek, S.J.Firbank, D.N.Bolam.

ABSTRACT

No abstract given.