PDBsum entry 4xml

Immune system

PDB id: 4xml

Contents

Protein chains

215 a.a.

218 a.a.

Waters ×33

PDB id:

4xml

Name:

Immune system

Title:

Crystal structure of fab of HIV-1 gp120 v3-specific human monoclonal antibody 2424

Structure:

Light chain of HIV-1 gp120 v3-specific human monoclonal antibody 2424. Chain: l. Engineered: yes. Heavy chain of HIV-1 gp120 v3-specific human monoclonal antibody 2424. Chain: h. Engineered: yes

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_taxid: 9606

Resolution:

2.68Å R-factor: 0.204 R-free: 0.285

Authors:

R.Pan,X.-P.Kong

Key ref:

R.Kumar et al. (2015). Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL. J Virol, 89, 9090-9102. PubMed id: 26109728 DOI: 10.1128/JVI.01280-15

Date:

14-Jan-15 Release date: 08-Jul-15

Protein chain

No UniProt id for this chain

Struc: 215 a.a.

Protein chain

No UniProt id for this chain

Struc: 218 a.a.

DOI no: 10.1128/JVI.01280-15

J Virol 89:9090-9102 (2015)

PubMed id: 26109728

Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.

R.Kumar, R.Pan, C.Upadhyay, L.Mayr, S.Cohen, X.H.Wang, P.Balasubramanian, A.Nádas, M.S.Seaman, S.Zolla-Pazner, M.K.Gorny, X.P.Kong, C.E.Hioe.

ABSTRACT

No abstract given.