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PDBsum entry 4ws9

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protein ligands Protein-protein interface(s) links
Transferase PDB id
4ws9

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
(+ 6 more) 391 a.a.
Ligands
PO4 ×18
Waters ×942
PDB id:
4ws9
Name: Transferase
Title: Crystal structure of smat n159g from sulfolobus solfataricus
Structure: S-adenosylmethionine synthase. Chain: a, b, c, d, e, f, g, h, i, j, k, l. Synonym: adomet synthase,methionine adenosyltransferase. Engineered: yes
Source: Sulfolobus solfataricus. Organism_taxid: 273057. Strain: atcc 35092 / dsm 1617 / jcm 11322 / p2. Gene: mat, sso0199. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.80Å     R-factor:   0.221     R-free:   0.256
Authors: F.Wang,E.L.Brady,S.Singh,J.A.Clinger,T.D.Huber,J.S.Thorson, G.N.Phillips Jr.
Key ref: E.L.Brady et al. Crystal structure of smat n159g from sulfolobus solfataricus.. To be published, .
Date:
26-Oct-14     Release date:   05-Nov-14    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q980S9  (METK_SULSO) -  S-adenosylmethionine synthase from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Seq:
Struc:
404 a.a.
391 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.5.1.6  - methionine adenosyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Methionine Adenosyltransferase
      Reaction: L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate
L-methionine
+ ATP
+ H2O
= S-adenosyl-L-methionine
+
phosphate
Bound ligand (Het Group name = PO4)
corresponds exactly
+ diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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