 |
PDBsum entry 4ws9
|
|
|
|
PDB id:
|
 |
|
 |
| Name: |
 |
Transferase
|
 |
|
Title:
|
 |
Crystal structure of smat n159g from sulfolobus solfataricus
|
|
Structure:
|
 |
S-adenosylmethionine synthase. Chain: a, b, c, d, e, f, g, h, i, j, k, l. Synonym: adomet synthase,methionine adenosyltransferase. Engineered: yes
|
|
Source:
|
 |
Sulfolobus solfataricus. Organism_taxid: 273057. Strain: atcc 35092 / dsm 1617 / jcm 11322 / p2. Gene: mat, sso0199. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
Resolution:
|
 |
|
2.80Å
|
R-factor:
|
0.221
|
R-free:
|
0.256
|
|
|
Authors:
|
 |
F.Wang,E.L.Brady,S.Singh,J.A.Clinger,T.D.Huber,J.S.Thorson, G.N.Phillips Jr.
|
|
Key ref:
|
 |
E.L.Brady
et al.
Crystal structure of smat n159g from sulfolobus solfataricus..
To be published,
.
|
 |
|
Date:
|
 |
|
26-Oct-14
|
Release date:
|
05-Nov-14
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
Headers
|
 |
|
|
References
|
|
|
|
|
|
|
Q980S9
(METK_SULSO) -
S-adenosylmethionine synthase from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
|
|
|
|
Seq: Struc:
|
 |
 |
 |
404 a.a.
391 a.a.*
|
|
|
|
|
|
|
|
|
 |
 |
|
|
Key: |
 |
PfamA domain |
 |
 |
 |
Secondary structure |
 |
 |
CATH domain |
 |
|
*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
|
|
|
|
|
 |
|
|
 |
 |
 |
 |
Enzyme class:
|
 |
E.C.2.5.1.6
- methionine adenosyltransferase.
|
|
 |
 |
 |
 |
 |

Pathway:
|
 |
Methionine Adenosyltransferase
|
 |
 |
 |
 |
 |
Reaction:
|
 |
L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate
|
 |
 |
 |
 |
 |
L-methionine
|
+
|
ATP
|
+
|
H2O
|
=
|
S-adenosyl-L-methionine
|
+
|
phosphate
Bound ligand (Het Group name = )
corresponds exactly
|
+
|
diphosphate
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
 |
');
}
}
 |