PDBsum entry 4ucd

Viral protein

PDB id: 4ucd

Contents

Protein chains

220 a.a.

Ligands

M81 ×2

SO4

Waters ×20

PDB id:

4ucd

Name:

Viral protein

Title:

N-terminal globular domain of the rsv nucleoprotein in complex with the nucleoprotein phosphoprotein interaction inhibitor m81

Structure:

Nucleoprotein. Chain: a, b. Fragment: n-terminal globular domain, residues 31-252. Synonym: protein n, nucleocapsid protein. Engineered: yes

Source:

Human respiratory syncytial virus a2. Organism_taxid: 11259. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

2.66Å R-factor: 0.178 R-free: 0.215

Authors:

M.Ouizougun-Oubari,N.Pereira,B.Tarus,M.Galloux,M.-A.Tortorici,S.Hoos, B.Baron,P.England,F.Bontems,F.A.Rey,J.-F.Eleouet,C.Sizun,A.Slama- Schwok,S.Duquerroy

Key ref:

M.Ouizougun-Oubari et al. (2015). A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus. J Virol, 89, 11129-11143. PubMed id: 26246564 DOI: 10.1128/JVI.01612-15

Date:

03-Dec-14 Release date: 19-Aug-15

Protein chains

P03418  (NCAP_HRSVA) -  Nucleoprotein from Human respiratory syncytial virus A (strain A2)

Seq: 391 a.a.

Struc: 220 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

DOI no: 10.1128/JVI.01612-15

J Virol 89:11129-11143 (2015)

PubMed id: 26246564

A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus.

M.Ouizougun-Oubari, N.Pereira, B.Tarus, M.Galloux, S.Lassoued, J.Fix, M.A.Tortorici, S.Hoos, B.Baron, P.England, D.Desmaële, P.Couvreur, F.Bontems, F.A.Rey, J.F.Eléouët, C.Sizun, A.Slama-Schwok, S.Duquerroy.

ABSTRACT

No abstract given.