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PDBsum entry 4mqb

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protein ligands Protein-protein interface(s) links
Transferase PDB id
4mqb

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
203 a.a.
Ligands
MES
PG4 ×2
Waters ×336
PDB id:
4mqb
Name: Transferase
Title: Crystal structure of thymidylate kinase from staphylococcus aureus in complex with 2-(n-morpholino)ethanesulfonic acid
Structure: Thymidylate kinase. Chain: a, b. Synonym: dtmp kinase. Engineered: yes
Source: Staphylococcus aureus. Organism_taxid: 158878. Strain: mu50. Gene: tmk, sav0482. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.55Å     R-factor:   0.145     R-free:   0.198
Authors: E.V.Filippova,G.Minasov,L.Shuvalova,O.Kiryukhina,R.Jedrzejczak, G.Babnigg,E.Rubin,J.Sacchettini,A.Joachimiak,W.F.Anderson,Midwest Center For Structural Genomics (Mcsg),Structures Of Mtb Proteins Conferring Susceptibility To Known Mtb Inhibitors (Mtbi)
Key ref: E.V.Filippova et al. Crystal structure of thymidylate kinase from staphylo aureus in complex with 2-(N-Morpholino)ethanesulfonic. To be published, .
Date:
16-Sep-13     Release date:   23-Oct-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P65248  (KTHY_STAAM) -  Thymidylate kinase from Staphylococcus aureus (strain Mu50 / ATCC 700699)
Seq:
Struc:
205 a.a.
203 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.4.9  - dTMP kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: dTMP + ATP = dTDP + ADP
dTMP
+ ATP
= dTDP
+ ADP
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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