 |
PDBsum entry 4jb3
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Hydrolase
|
|
|
Title:
|
|
Crystal structure of bt_0970, a had family phosphatase from bacteroides thetaiotaomicron vpi-5482, target efi-501083, with bound sodium and glycerol, closed lid, ordered loop
|
|
Structure:
|
|
Haloacid dehalogenase-like hydrolase. Chain: a. Engineered: yes
|
|
Source:
|
|
Bacteroides thetaiotaomicron. Organism_taxid: 226186. Strain: vpi-5482. Gene: bt_0970. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
Resolution:
|
|
|
1.50Å
|
R-factor:
|
0.147
|
R-free:
|
0.172
|
|
|
Authors:
|
|
M.W.Vetting,R.Toro,R.Bhosle,P.R.Kumar,A.Ghosh,N.F.Al Obaidi,M.Stead, E.Washington,A.Scott Glenn,S.Chowdhury,B.Evans,J.Hammonds, B.Hillerich,J.Love,R.D.Seidel,H.J.Imker,D.Dunaway-Mariano,K.N.Allen, J.A.Gerlt,S.C.Almo,Enzyme Function Initiative (Efi)
|
|
Key ref:
|
|
M.W.Vetting
et al.
Crystal structure of bt_0970, A had family phosphatas bacteroides thetaiotaomicron vpi-5482, Target efi-501 with bound sodium and glycerol, Closed lid, Ordered l.
To be published,
.
|
|
|
Date:
|
|
|
19-Feb-13
|
Release date:
|
13-Mar-13
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q8A947
(RIBX_BACTN) -
D-ribitol-5-phosphate phosphatase from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
|
|
|
|
Seq:
Struc:
|
|
|
|
206 a.a.
218 a.a.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.3.1.3.104
- 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase.
|
|
|
|
|
|
|
Reaction:
|
|
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O = 5-amino-6- (D-ribitylamino)uracil + phosphate
|
|
|
|
|
|
5-amino-6-(5-phospho-D-ribitylamino)uracil
|
+
|
H2O
|
=
|
5-amino-6- (D-ribitylamino)uracil
|
+
|
phosphate
|
|
|
|
|
|
|
|
|
|
Cofactor:
|
|
Mg(2+)
|
|
|
|
|
|
|
|
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
|
|
Links
