PDBsum entry 4gio

Unknown function

PDB id: 4gio

Contents

Protein chains

96 a.a.

Metals

_BR ×3

Waters ×133

PDB id:

4gio

Name:

Unknown function

Title:

Crystal structure of campylobacter jejuni cj0090

Structure:

Putative lipoprotein. Chain: a, b. Fragment: unp residues 16-122. Engineered: yes

Source:

Campylobacter jejuni subsp. Jejuni. Organism_taxid: 192222. Strain: nctc 11168. Atcc: 700819. Gene: cj0090. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.90Å R-factor: 0.198 R-free: 0.244

Authors:

F.Kawai,H.J.Yeo

Key ref:

S.Paek et al. (2012). Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins. Proteins, 80, 2804-2809. PubMed id: 22987763

Date:

08-Aug-12 Release date: 26-Sep-12

Protein chains

Q0PC47  (Q0PC47_CAMJE) -  Lipoprotein from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

Seq: 122 a.a.

Struc: 96 a.a.

Enzyme reactions

• Enzyme class: E.C.?

Proteins 80:2804-2809 (2012)

PubMed id: 22987763

Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins.

S.Paek, F.Kawai, K.J.Choi, H.J.Yeo.

ABSTRACT

Bacterial lipoproteins play an important role in bacterial pathogenesis and physiology. The genome of Campylobacter jejuni, a major foodborn pathogen, is predicted to contain over 20 lipoproteins. However, the functions of the majority of C. jejuni lipoproteins remain unknown. The Cj0090 protein is encoded by a lipoprotein operon composed of cj0089, cj0090, and cj0091. Here, we report the crystal structure of Cj0090 at 1.9 Å resolution, revealing a novel variant of the immunoglobulin fold with β-sandwich architecture. The structure suggests that Cj0090 may be involved in protein-protein interactions, consistent with a possible role for bacterial lipoproteins. Proteins 2012;. © 2012 Wiley Periodicals, Inc.