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PDBsum entry 4g8t

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protein ligands metals Protein-protein interface(s) links
Lyase PDB id
4g8t

 

 

 

 

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Contents
Protein chains
441 a.a.
Ligands
SO4 ×4
GOL ×7
DTU
DTT ×3
Metals
_NA ×4
Waters ×1973
PDB id:
4g8t
Name: Lyase
Title: Crystal structure of a glucarate dehydratase related protein, from actinobacillus succinogenes, target efi-502312, with sodium and sulfate bound, ordered loop
Structure: Glucarate dehydratase. Chain: a, b, c, d. Engineered: yes
Source: Actinobacillus succinogenes. Organism_taxid: 339671. Strain: 130z. Gene: asuc_1847. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.70Å     R-factor:   0.154     R-free:   0.179
Authors: M.W.Vetting,R.Toro,R.Bhosle,N.F.Al Obaidi,L.L.Morisco,S.R.Wasserman, S.Sojitra,E.Washington,A.Scott Glenn,S.Chowdhury,B.Evans,J.Hammonds, B.Hillerich,J.Love,R.D.Seidel,H.J.Imker,J.A.Gerlt,S.C.Almo,Enzyme Function Initiative (Efi)
Key ref: M.W.Vetting et al. Crystal structure of a glucarate dehydratase related protein, From actinobacillus succinogenes, Target efi-502312, With sodium and sulfate bound, Ordered lo. To be published, .
Date:
23-Jul-12     Release date:   15-Aug-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
A6VQF1  (A6VQF1_ACTSZ) -  glucarate dehydratase from Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z)
Seq:
Struc:
442 a.a.
441 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.40  - glucarate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O
D-glucarate
=
5-dehydro-4-deoxy-D-glucarate
Bound ligand (Het Group name = GOL)
matches with 46.15% similarity
+ H2O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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