PDBsum entry 4dll

Oxidoreductase

PDB id: 4dll

Contents

Protein chains

288 a.a.

Ligands

SO4 ×2

Waters ×115

PDB id:

4dll

Name:

Oxidoreductase

Title:

Crystal structure of a 2-hydroxy-3-oxopropionate reductase from polaromonas sp. Js666

Structure:

2-hydroxy-3-oxopropionate reductase. Chain: a, b. Fragment: 2-hydroxy-3-oxopropionate reductase. Engineered: yes

Source:

Polaromonas sp. Js666. Organism_taxid: 296591. Strain: js666 / atcc baa-500. Gene: bpro_1712. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.11Å R-factor: 0.221 R-free: 0.278

Authors:

R.Agarwal,S.Chamala,B.Evans,R.Foti,A.Gizzi,B.Hillerich,A.Kar, J.Lafleur,R.Seidel,G.Villigas,W.Zencheck,S.C.Almo,S.Swaminathan,New York Structural Genomics Research Consortium (Nysgrc)

Key ref:

R.Agarwal et al. Crystal structure of a 2-Hydroxy-3-Oxopropionate redu from polaromonas sp. Js666. To be published, .

Date:

06-Feb-12 Release date: 15-Feb-12

Protein chains

Q12CU4  (Q12CU4_POLSJ) -  2-hydroxy-3-oxopropionate reductase from Polaromonas sp. (strain JS666 / ATCC BAA-500)

Seq: 298 a.a.

Struc: 288 a.a.

Enzyme reactions

• Enzyme class: E.C.1.1.1.60 - 2-hydroxy-3-oxopropionate reductase.
• Reaction:
  1. (R)-glycerate + NADP⁺ = 2-hydroxy-3-oxopropanoate + NADPH + H⁺
  2. (R)-glycerate + NAD⁺ = 2-hydroxy-3-oxopropanoate + NADH + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site