PDBsum entry 4dg9

Ligase/inhibitor

PDB id: 4dg9

Contents

Protein chain

575 a.a.

Ligands

DG9

Waters ×117

PDB id:

4dg9

Name:

Ligase/inhibitor

Title:

Structure of holo-pa1221, an nrps protein containing adenylation and pcp domains bound to vinylsulfonamide inhibitor

Structure:

Pa1221. Chain: a. Engineered: yes

Source:

Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pa01. Gene: pa1221. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.55Å R-factor: 0.185 R-free: 0.237

Authors:

C.A.Mitchell,C.Shi,C.C.Aldrich,A.M.Gulick

Key ref:

C.A.Mitchell et al. (2012). Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains. Biochemistry, 51, 3252-3263. PubMed id: 22452656

Date:

25-Jan-12 Release date: 02-May-12

Protein chain

Q9I4B7  (Q9I4B7_PSEAE) -  Carrier domain-containing protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

Seq: 618 a.a.

Struc: 575 a.a.

Enzyme reactions

• Enzyme class: E.C.6.2.1.- - ?????

Biochemistry 51:3252-3263 (2012)

PubMed id: 22452656

Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains.

C.A.Mitchell, C.Shi, C.C.Aldrich, A.M.Gulick.

ABSTRACT

No abstract given.