PDBsum entry 4ba2

Hydrolase/RNA

PDB id: 4ba2

Contents

Protein chains

274 a.a.

234 a.a.

213 a.a.

DNA/RNA

Ligands

1PE

PO4 ×2

Metals

_NA

Waters ×105

PDB id:

4ba2

Name:

Hydrolase/RNA

Title:

Archaeal exosome (rrp4-rrp41(d182a)-rrp42) bound to inorganic phosphate

Structure:

Probable exosome complex exonuclease 2. Chain: a. Synonym: rrp42. Engineered: yes. Probable exosome complex exonuclease 1. Chain: b. Synonym: rrp41. Engineered: yes. Mutation: yes.

Source:

Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli. Expression_system_taxid: 83333. Synthetic: yes. Organism_taxid: 2287

Resolution:

2.50Å R-factor: 0.189 R-free: 0.259

Authors:

E.Lorentzen,E.Conti

Key ref:

E.Lorentzen and E.Conti (2012). Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction. Archaea, 2012, 721869. PubMed id: 23319881

Date:

10-Sep-12 Release date: 03-Oct-12

Protein chain

Q9UXC0  (RRP42_SULSO) -  Exosome complex component Rrp42 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Seq: 275 a.a.

Struc: 274 a.a.

Protein chain

Q9UXC2  (RRP41_SULSO) -  Exosome complex component Rrp41 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Seq: 248 a.a.

Struc: 234 a.a.*

Protein chain

Q9UXC4  (RRP4_SACS2) -  Exosome complex component Rrp4 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Seq: 249 a.a.

Struc: 213 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

DNA/RNA chain

A-A-A-A 4 bases

Enzyme reactions

• Enzyme class: Chain B: E.C.3.1.13.- - ?????

Archaea 2012:721869 (2012)

PubMed id: 23319881

Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction.

E.Lorentzen, E.Conti.

ABSTRACT

No abstract given.