PDBsum entry 4aib

Lyase

PDB id: 4aib

Contents

Protein chains

339 a.a.

Waters ×101

PDB id:

4aib

Name:

Lyase

Title:

Crystal structure of ornithine decarboxylase from entamoeba histolytica.

Structure:

Ornithine decarboxylase. Chain: a, b, c, d. Engineered: yes

Source:

Entamoeba histolytica. Organism_taxid: 294381. Strain: hm-1\:imss. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.87Å R-factor: 0.253 R-free: 0.299

Authors:

P.Preeti,P.Kumar,S.Tomar

Key ref:

Preeti et al. (2013). Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution. Plos One, 8, e53397. PubMed id: 23326423

Date:

09-Feb-12 Release date: 30-Jan-13

Protein chains

Q58P26  (Q58P26_ENTHI) -  ornithine decarboxylase from Entamoeba histolytica

Seq: 413 a.a.

Struc: 339 a.a.

Enzyme reactions

• Enzyme class: E.C.4.1.1.17 - ornithine decarboxylase.
• Pathway: Spermine Biosynthesis
• Reaction: L-ornithine + H⁺ = putrescine + CO2
• Cofactor: Pyridoxal 5'-phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Plos One 8:e53397 (2013)

PubMed id: 23326423

Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.

Preeti, S.Tapas, P.Kumar, R.Madhubala, S.Tomar.

ABSTRACT

No abstract given.