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PDBsum entry 3w6h
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PDB id:
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Lyase
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Title:
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Crystal structure of 19f probe-labeled hcai in complex with acetazolamide
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Structure:
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Carbonic anhydrase 1. Chain: a, b. Synonym: carbonate dehydratase i, carbonic anhydrase b, cab, carbonic anhydrase i, ca-i. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.96Å
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R-factor:
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0.228
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R-free:
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0.283
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Authors:
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Y.Takaoka,Y.Kioi,A.Morito,J.Otani,K.Arita,E.Ashihara,M.Ariyoshi, H.Tochio,M.Shirakawa,I.Hamachi
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Key ref:
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Y.Takaoka
et al.
Quantitative comparison of protein dynamics in live c and in vitro by in-Cell 19f-Nmr.
To be published,
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Date:
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14-Feb-13
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Release date:
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13-Mar-13
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PROCHECK
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Headers
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References
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P00915
(CAH1_HUMAN) -
Carbonic anhydrase 1 from Homo sapiens
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Seq:
Struc:
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261 a.a.
256 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class 2:
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E.C.4.2.1.1
- carbonic anhydrase.
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Reaction:
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hydrogencarbonate + H+ = CO2 + H2O
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hydrogencarbonate
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+
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H(+)
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=
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CO2
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+
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H2O
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Cofactor:
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Zn(2+)
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Enzyme class 3:
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E.C.4.2.1.69
- cyanamide hydratase.
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Reaction:
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urea = cyanamide + H2O
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urea
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=
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cyanamide
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+
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H2O
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
