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PDBsum entry 3vn4
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PDB id:
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Hydrolase
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Title:
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Crystal structure of the exosite-containing fragment of human adamts13 (p475s mutant)
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Structure:
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A disintegrin and metalloproteinase with thrombospondin motifs 13. Chain: a. Fragment: dtcs domains, unp residues 287-685. Synonym: adam-ts 13, adam-ts13, adamts-13, von willebrand factor- cleaving protease, vwf-cp, vwf-cleaving protease. Engineered: yes. Mutation: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: adamts13. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: hek293s gnt1-.
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Resolution:
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2.80Å
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R-factor:
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0.232
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R-free:
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0.277
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Authors:
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D.Nakayama,M.Akiyama,S.Takeda,K.Kokame,J.Takagi,T.Miyata
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Key ref:
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D.Nakayama
et al.
Structural analysis and biochemical studies of adamts p475s mutant.
To be published,
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PubMed id:
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Date:
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21-Dec-11
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Release date:
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26-Dec-12
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PROCHECK
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Headers
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References
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Q76LX8
(ATS13_HUMAN) -
A disintegrin and metalloproteinase with thrombospondin motifs 13 from Homo sapiens
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Seq:
Struc:
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1427 a.a.
375 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Links
