PDBsum entry 3vfs

Immune system

PDB id: 3vfs

Contents

Protein chains

276 a.a.

99 a.a.

13 a.a.

Waters ×575

PDB id:

3vfs

Name:

Immune system

Title:

Crystal structure of hla b 3508Lpep-p5ala , peptide mutant p5-ala

Structure:

Mhc class i antigen. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Synonym: beta-2-microglobulin form pi 5.3. Engineered: yes. Lpep peptide from ebv, p5a, lpepapqgqltay. Chain: c.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Other_details: gl biochem

Resolution:

1.85Å R-factor: 0.173 R-free: 0.216

Authors:

Y.C.Liu,J.Rossjohn,S.Gras

Key ref:

Y.C.Liu et al. (2012). The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule. J Biol Chem, 287, 12267-12276. PubMed id: 22343629

Date:

10-Jan-12 Release date: 22-Feb-12

Protein chain

C5MK56  (C5MK56_HUMAN) -  HLA-B*3507 from Homo sapiens

Seq: 362 a.a.

Struc: 276 a.a.

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 99 a.a.

Protein chain

No UniProt id for this chain

Struc: 13 a.a.

J Biol Chem 287:12267-12276 (2012)

PubMed id: 22343629

The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule.

Y.C.Liu, Z.Chen, S.R.Burrows, A.W.Purcell, J.McCluskey, J.Rossjohn, S.Gras.

ABSTRACT

No abstract given.