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PDBsum entry 3v8m
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PDB id:
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Transferase
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Title:
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Crystal structure of NAD kinase 1 from listeria monocytogenes in complexe with 5'-azido-8-bromo-5'-deoxyadenosine
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Structure:
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Probable inorganic polyphosphate/atp-NAD kinase 1. Chain: a. Synonym: poly(p)/atp NAD kinase 1. Engineered: yes
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Source:
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Listeria monocytogenes. Organism_taxid: 1639. Gene: ppnk1, lmo0968. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.48Å
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R-factor:
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0.205
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R-free:
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0.237
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Authors:
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M.Gelin,G.Poncet-Montange,L.Assairi,L.Morellato,V.Huteau,L.Dugu, O.Dussurget,S.Pochet,G.Labesse
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Key ref:
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M.Gelin
et al.
(2012).
Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.
Structure,
20,
1107-1117.
PubMed id:
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Date:
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23-Dec-11
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Release date:
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14-Mar-12
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PROCHECK
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Headers
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References
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Q8Y8D7
(NADK1_LISMO) -
NAD kinase 1 from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
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Seq:
Struc:
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264 a.a.
257 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.1.23
- NAD(+) kinase.
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Reaction:
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NAD+ + ATP = ADP + NADP+ + H+
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NAD(+)
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+
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ATP
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=
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ADP
Bound ligand (Het Group name = )
matches with 58.06% similarity
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NADP(+)
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Structure
20:1107-1117
(2012)
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PubMed id:
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Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.
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M.Gelin,
G.Poncet-Montange,
L.Assairi,
L.Morellato,
V.Huteau,
L.Dugué,
O.Dussurget,
S.Pochet,
G.Labesse.
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ABSTRACT
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Links
