PDBsum entry 3v1g

Hormone

PDB id: 3v1g

Contents

Protein chains

21 a.a.

30 a.a.

Ligands

IPH

Metals

_ZN ×2

_CL

Waters ×81

PDB id:

3v1g

Name:

Hormone

Title:

Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health

Structure:

Insulin. Chain: a, c. Engineered: yes. Insulin. Chain: b, d. Engineered: yes

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606

Resolution:

2.20Å R-factor: 0.229 R-free: 0.323

Authors:

Z.L.Wan,Q.X.Hua,N.P.Wickramasinghe,K.Huang,A.T.Petkova,S.Q.Hu, N.B.Phillips,I.J.Yeh,J.Whittake,F.Ismail-Beigi,P.G.Katsoyyannis, R.Tycko,M.A.Weiss

Key ref:

Z.L.Wan et al. Forestalling insulin fibrillation by insertion of a c clamp mechanism-Based application of protein engineer global health. To be published, .

Date:

09-Dec-11 Release date: 12-Dec-12

Protein chains

P01308  (INS_HUMAN) -  Insulin from Homo sapiens

Seq: 110 a.a.

Struc: 21 a.a.

Protein chains

P01308  (INS_HUMAN) -  Insulin from Homo sapiens

Seq: 110 a.a.

Struc: 30 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)