PDBsum entry 3uvh

Transport protein

PDB id: 3uvh

Contents

Protein chains

231 a.a.

Waters ×439

PDB id:

3uvh

Name:

Transport protein

Title:

Crystal structure analysis of e81m mutant of human clic1

Structure:

Chloride intracellular channel protein 1. Chain: a, b. Synonym: chloride channel abp, nuclear chloride ion channel 27, ncc27, regulatory nuclear chloride ion channel protein, hrncc. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: clic1, g6, ncc27. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.84Å R-factor: 0.204 R-free: 0.258

Authors:

S.Fanucchi,I.A.Achilonu,M.A.Fernandes,D.A.Legg-E'Silva,S.H.Stoychev, H.W.Dirr

Key ref:

D.A.Legg-E'Silva et al. Crystal structure analysis of e81m mutant of human cl. To be published, .

Date:

30-Nov-11 Release date: 14-Dec-11

Protein chains

O00299  (CLIC1_HUMAN) -  Chloride intracellular channel protein 1 from Homo sapiens

Seq: 241 a.a.

Struc: 231 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class 2: E.C.1.8.-.-
• Enzyme class 3: E.C.1.8.5.1 - glutathione dehydrogenase (ascorbate).
• Reaction: L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site