PDBsum entry 3uth

Isomerase

PDB id

3uth

Loading ...

Contents

			Protein chains

					505 a.a.

			Ligands

					FDA ×4


					SO4 ×12


					GDU ×2

			Waters ×659

PDB id:

3uth

Links

Name:

Isomerase

Title:

Crystal structure of aspergillus fumigatus udp galactopyranose mutase complexed with substrate udp-galp in reduced state

Structure:

Udp-galactopyranose mutase. Chain: a, b, c, d. Engineered: yes. Mutation: yes

Source:

Aspergillus fumigatus. Organism_taxid: 746128. Gene: glf, glfa. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.25Å

R-factor:

0.187

R-free:

0.211

Authors:

R.Dhatwalia,H.Singh,J.J.Tanner

Key ref:

R.Dhatwalia et al. (2012). Crystal structures and small-angle x-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus. J Biol Chem, 287, 9041-9051. PubMed id: 22294687

Date:

25-Nov-11

Release date:

08-Feb-12

PROCHECK

	Headers

	References

Protein chains

Q4W1X2 (GLFA_ASPFM) - UDP-galactopyranose mutase from Aspergillus fumigatus

Seq: Struc:					510 a.a. 505 a.a.*

Key:

PfamA domain

Secondary structure

CATH domain

* PDB and UniProt seqs differ at 3 residue positions (black crosses)



		Enzyme reactions

Enzyme class:

E.C.5.4.99.9 - UDP-galactopyranose mutase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Pathway:

UDP-glucose, UDP-galactose and UDP-glucuronate Biosynthesis

Reaction:

UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose

UDP-D-galactopyranose	=	UDP-D-galacto-1,4-furanose

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

Added reference

	J Biol Chem 287:9041-9051 (2012)
PubMed id: 22294687

Crystal structures and small-angle x-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus.
R.Dhatwalia, H.Singh, M.Oppenheimer, D.B.Karr, J.C.Nix, P.Sobrado, J.J.Tanner.

ABSTRACT

No abstract given.