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PDBsum entry 3us4
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protein ligands links
Transferase PDB id
3us4

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
97 a.a.
Ligands
SO4 ×2
Waters ×72
PDB id:
3us4
Name: Transferase
Title: Crystal structure of a sh2 domain of a megakaryocyte-associated tyrosine kinase (matk) from homo sapiens at 1.50 a resolution
Structure: Megakaryocyte-associated tyrosine-protein kinase. Chain: a. Fragment: sh2 domain residues 117-213. Synonym: hematopoietic consensus tyrosine-lacking kinase, protein kinase hyl, tyrosine-protein kinase ctk. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ctk, hyl, matk, nm_139355. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.50Å     R-factor:   0.187     R-free:   0.208
Authors: Joint Center For Structural Genomics (Jcsg),Partnership For T-Cell Biology (Tcell)
Key ref: Joint center for structural genomics (jcsg) and partnership for t-cell biology Crystal structure of a sh2 domain of a megakaryocyte-Associated tyrosine kinase (matk) from sapiens at 1.50 a resolution. To be published, .
Date:
22-Nov-11     Release date:   28-Dec-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P42679  (MATK_HUMAN) -  Megakaryocyte-associated tyrosine-protein kinase from Homo sapiens
Seq:
Struc: 		507 a.a.
97 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.2  - non-specific protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
 + ATP
 = O-phospho-L-tyrosyl-[protein]
 + ADP
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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