spacer
spacer

PDBsum entry 3uec

Go to PDB code: 
protein ligands metals links
Cell cycle PDB id
3uec

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chain
138 a.a.
Ligands
ALA-ARG-TPO-LYS
EDO ×2
PG4
1PE
ACT
PEG
Metals
_ZN
Waters ×53
PDB id:
3uec
Name: Cell cycle
Title: Crystal structure of human survivin bound to histone h3 phosphorylated on threonine-3.
Structure: Baculoviral iap repeat-containing protein 5. Chain: a. Synonym: apoptosis inhibitor 4, apoptosis inhibitor survivin. Engineered: yes. Mutation: yes. N-terminal fragment of histone h3. Chain: b. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api4, birc5, iap4. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes
Resolution:
2.18Å     R-factor:   0.199     R-free:   0.215
Authors: E.Niedzialkowska,P.J.Porebski,D.R.Cooper,M.Chruszcz,F.Wang, J.M.Higgins,P.T.Stukenberg,W.Minor
Key ref: E.Niedzialkowska et al. (2012). Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol Biol Cell, 23, 1457-1466. PubMed id: 22357620
Date:
30-Oct-11     Release date:   07-Mar-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
O15392  (BIRC5_HUMAN) -  Baculoviral IAP repeat-containing protein 5 from Homo sapiens
Seq:
Struc:
142 a.a.
138 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
Mol Biol Cell 23:1457-1466 (2012)
PubMed id: 22357620  
 
 
Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
E.Niedzialkowska, F.Wang, P.J.Porebski, W.Minor, J.M.Higgins, P.T.Stukenberg.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23211769 C.A.Musselman, M.E.Lalonde, J.Côté, and T.G.Kutateladze (2012).
Perceiving the epigenetic landscape through histone readers.
  Nat Struct Mol Biol, 19, 1218-1227.  
23175282 M.Carmena, M.Wheelock, H.Funabiki, and W.C.Earnshaw (2012).
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.
  Nat Rev Mol Cell Biol, 13, 789-803.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

spacer

spacer