PDBsum entry 3s6c

Immune system, lipid binding protein

PDB id: 3s6c

Contents

Protein chain

372 a.a.

Ligands

NAG-FUC

GOL

PDB id:

3s6c

Name:

Immune system, lipid binding protein

Title:

Structure of human cd1e

Structure:

Beta-2-microglobulin, t-cell surface glycoprotein cd1e, membrane-associated. Chain: a. Fragment: p61769 residues 21-119, p15812 residues 32-303. Engineered: yes. Other_details: fusion of beta-2 microglobulin and cd1e heavy chain

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: b2m, cd1e. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: m10.

Resolution:

2.90Å R-factor: 0.243 R-free: 0.296

Authors:

L.F.Garcia-Alles,L.Maveyraud,S.Tranier,L.Mourey

Key ref:

L.F.Garcia-Alles et al. (2011). Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes. Proc Natl Acad Sci U S A, 108, 13230-13235. PubMed id: 21788486

Date:

25-May-11 Release date: 20-Jul-11

Protein chain

P15812  (CD1E_HUMAN) -  T-cell surface glycoprotein CD1e, membrane-associated from Homo sapiens

Seq: 388 a.a.

Struc: 372 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 372 a.a.

* PDB and UniProt seqs differ at 37 residue positions (black crosses)

Proc Natl Acad Sci U S A 108:13230-13235 (2011)

PubMed id: 21788486

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes.

L.F.Garcia-Alles, G.Giacometti, C.Versluis, L.Maveyraud, D.de Paepe, J.Guiard, S.Tranier, M.Gilleron, J.Prandi, D.Hanau, A.J.Heck, L.Mori, G.De Libero, G.Puzo, L.Mourey, H.de la Salle.

ABSTRACT

No abstract given.