PDBsum entry 3qxr

DNA

PDB id: 3qxr

Contents

DNA/RNA

Metals

_MG ×2

__K ×9

Waters ×211

PDB id:

3qxr

Name:

DNA

Title:

Crystal structure of the brominated ckit-1 proto-oncogene promoter quadruplex DNA

Structure:

5'-d( Ap Gp Gp Gp Ap Gp Gp Gp Cp Gp Cp (Bru) p Gp Gp Gp Ap Gp Gp Ap Gp Gp G)-3'. Chain: a, b. Engineered: yes

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606

Resolution:

1.62Å R-factor: 0.168 R-free: 0.213

Authors:

D.Wei,G.N.Parkinson,S.Neidle

Key ref:

D.Wei et al. (2012). Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation. Nucleic Acids Res, 40, 4691-4700. PubMed id: 22287624

Date:

02-Mar-11 Release date: 18-Jan-12

DNA/RNA chains

A-G-G-G-A-G-G-G-C-G-C-BRU-G-G-G-A-G-G-A-G-G-G 22 bases

A-G-G-G-A-G-G-G-C-G-C-BRU-G-G-G-A-G-G-A-G-G-G 22 bases

Nucleic Acids Res 40:4691-4700 (2012)

PubMed id: 22287624

Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation.

D.Wei, G.N.Parkinson, A.P.Reszka, S.Neidle.

ABSTRACT

No abstract given.