PDBsum entry 3qwz

Transport protein

PDB id: 3qwz

Contents

Protein chains

177 a.a.

81 a.a.

Waters ×163

PDB id:

3qwz

Name:

Transport protein

Title:

Crystal structure of faf1 ubx-p97n-domain complex

Structure:

Transitional endoplasmic reticulum atpase. Chain: a. Fragment: unp residues 1-208. Synonym: ter atpase, 15s mg(2+)-atpase p97 subunit, valosin- containing protein, vcp. Engineered: yes. Fas-associated factor 1. Chain: b. Fragment: faf1 ubx domain, unp residues 571-650.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: faf1, ubxd12, ubxn3a, cgi-03.

Resolution:

2.00Å R-factor: 0.225 R-free: 0.249

Authors:

J.K.Park,H.Jeon,J.J.Lee,K.H.Kim,K.J.Lee,E.E.Kim

Key ref:

J.K.Park et al. Dissection of the interaction between faf1 ubx and p9. To be published, .

Date:

28-Feb-11 Release date: 09-May-12

Protein chain

P55072  (TERA_HUMAN) -  Transitional endoplasmic reticulum ATPase from Homo sapiens

Seq: 806 a.a.

Struc: 177 a.a.*

Protein chain

Q9UNN5  (FAF1_HUMAN) -  FAS-associated factor 1 from Homo sapiens

Seq: 650 a.a.

Struc: 81 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)

Enzyme reactions

• Enzyme class 2: Chain A: E.C.3.6.4.6 - vesicle-fusing ATPase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺
• Enzyme class 3: Chain B: E.C.?

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site