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PDBsum entry 3qtt
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PDB id:
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Ligase
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Title:
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Crystal structure of pantoate-beta-alanine ligase from francisella tularensis complexed with beta-gamma atp and beta-alanine
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Structure:
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Pantothenate synthetase. Chain: a, b. Synonym: ps, pantoate--beta-alanine ligase, pantoate-activating enzyme. Engineered: yes
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Source:
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Francisella tularensis subsp. Tularensis. Organism_taxid: 119856. Strain: schu s4. Gene: ftt_1390, panc. Expressed in: escherichia coli. Expression_system_taxid: 511693.
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Resolution:
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2.60Å
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R-factor:
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0.176
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R-free:
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0.251
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Authors:
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N.Maltseva,Y.Kim,K.Kwon,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)
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Key ref:
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N.Maltseva
et al.
Crystal structure of pantoate-Beta-Alanine ligase fro francisella tularensis complexed with beta-Gamma ATP beta-Alanine..
To be published,
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Date:
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23-Feb-11
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Release date:
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23-Mar-11
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PROCHECK
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Headers
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References
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Q5NF57
(PANC_FRATT) -
Pantothenate synthetase from Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
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Seq:
Struc:
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261 a.a.
261 a.a.
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Key: |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.6.3.2.1
- pantoate--beta-alanine ligase (AMP-forming).
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Pathway:
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Coenzyme A Biosynthesis (early stages)
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Reaction:
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(R)-pantoate + beta-alanine + ATP = (R)-pantothenate + AMP + diphosphate + H+
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(R)-pantoate
Bound ligand (Het Group name = )
matches with 50.00% similarity
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beta-alanine
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ATP
Bound ligand (Het Group name = )
corresponds exactly
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(R)-pantothenate
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+
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AMP
Bound ligand (Het Group name = )
matches with 74.19% similarity
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diphosphate
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
