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PDBsum entry 3p8c
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Protein binding
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PDB id
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3p8c
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Contents |
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1175 a.a.
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1086 a.a.
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204 a.a.
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64 a.a.
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156 a.a.
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* Residue conservation analysis
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PDB id:
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| Name: |
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Protein binding
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Title:
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Structure and control of the actin regulatory wave complex
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Structure:
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Cytoplasmic fmr1-interacting protein 1. Chain: a. Synonym: specifically rac1-associated protein 1, sra-1, p140sra-1. Engineered: yes. Nck-associated protein 1. Chain: b. Synonym: nap 1, membrane-associated protein hem-2, p125nap1. Engineered: yes. Wiskott-aldrich syndrome protein family member 1.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: cyfip1, kiaa0068. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: nckap1, hem2, kiaa0587, nap1. Gene: wasf1, kiaa0269, scar1, wave1. Expressed in: escherichia coli.
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Resolution:
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2.29Å
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R-factor:
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0.191
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R-free:
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0.237
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Authors:
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Z.Chen,D.Borek,S.B.Padrick,T.S.Gomez,Z.Metlagel,A.M.Ismail,J.Umetani, D.D.Billadeau,Z.Otwinowski,M.K.Rosen
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Key ref:
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Z.Chen
et al.
(2010).
Structure and control of the actin regulatory WAVE complex.
Nature,
468,
533-538.
PubMed id:
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Date:
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13-Oct-10
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Release date:
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01-Dec-10
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PROCHECK
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Headers
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References
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Q7L576
(CYFP1_HUMAN) -
Cytoplasmic FMR1-interacting protein 1 from Homo sapiens
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Seq:
Struc:
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1253 a.a.
1175 a.a.
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Q9Y2A7
(NCKP1_HUMAN) -
Nck-associated protein 1 from Homo sapiens
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Seq:
Struc:
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1128 a.a.
1086 a.a.
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Q92558
(WASF1_HUMAN) -
Actin-binding protein WASF1 from Homo sapiens
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Seq:
Struc:
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559 a.a.
204 a.a.*
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Nature
468:533-538
(2010)
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PubMed id:
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Structure and control of the actin regulatory WAVE complex.
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Z.Chen,
D.Borek,
S.B.Padrick,
T.S.Gomez,
Z.Metlagel,
A.M.Ismail,
J.Umetani,
D.D.Billadeau,
Z.Otwinowski,
M.K.Rosen.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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J.D.Rotty,
C.Wu,
and
J.E.Bear
(2012).
New insights into the regulation and cellular functions of the ARP2/3 complex.
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Nat Rev Mol Cell Biol,
14,
7.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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