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PDBsum entry 3ozu
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Lipid binding protein
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PDB id
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3ozu
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PDB id:
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| Name: |
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Lipid binding protein
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Title:
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The crystal structure of flavohemoglobin from r. Eutrophus in complex with miconazole
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Structure:
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Flavohemoprotein. Chain: a. Synonym: hemoglobin-like protein, flavohemoglobin, fhp, nitric oxide dioxygenase, no oxygenase, nod. Engineered: yes
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Source:
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Ralstonia eutropha. Cupriavidus necator. Organism_taxid: 381666. Strain: h16. Gene: hmp, fhp, phg200. Expressed in: escherichia coli. Expression_system_taxid: 511693.
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Resolution:
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2.00Å
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R-factor:
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0.188
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R-free:
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0.233
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Authors:
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E.El Hammi,E.Warkentin,U.Demmer,U.Ermler,L.Baciou
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Key ref:
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E.El Hammi
et al.
(2011).
Structure of Ralstonia eutropha flavohemoglobin in complex with three antibiotic azole compounds.
Biochemistry,
50,
1255-1264.
PubMed id:
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Date:
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27-Sep-10
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Release date:
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16-Mar-11
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PROCHECK
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Headers
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References
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P39662
(HMP_CUPNH) -
Flavohemoprotein from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)
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Seq:
Struc:
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403 a.a.
403 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.1.14.12.17
- nitric oxide dioxygenase.
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Reaction:
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1.
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2 nitric oxide + NADPH + 2 O2 = 2 nitrate + NADP+ + H+
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2.
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2 nitric oxide + NADH + 2 O2 = 2 nitrate + NAD+ + H+
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2
×
nitric oxide
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+
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NADPH
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+
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2
×
O2
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=
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2
×
nitrate
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+
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NADP(+)
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+
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H(+)
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2
×
nitric oxide
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+
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NADH
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+
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2
×
O2
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=
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2
×
nitrate
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+
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NAD(+)
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+
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H(+)
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Cofactor:
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FAD; Heme
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FAD
Bound ligand (Het Group name =
FAD)
corresponds exactly
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Heme
Bound ligand (Het Group name =
HEM)
matches with 95.45% similarity
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Biochemistry
50:1255-1264
(2011)
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PubMed id:
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Structure of Ralstonia eutropha flavohemoglobin in complex with three antibiotic azole compounds.
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E.El Hammi,
E.Warkentin,
U.Demmer,
F.Limam,
N.M.Marzouki,
U.Ermler,
L.Baciou.
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ABSTRACT
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Links
