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PDBsum entry 3o8h
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Transcription
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PDB id
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3o8h
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Transcription
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Title:
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Ethr from mycobacterium tuberculosis in complex with compound bdm14950
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Structure:
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Transcriptional regulatory repressor protein (tetr-family) ethr. Chain: a. Synonym: transcriptional regulator, tetr family. Engineered: yes
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Source:
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Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ethr, mt3970, rv3855. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.90Å
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R-factor:
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0.197
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R-free:
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0.251
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Authors:
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N.Willand,M.Desroses,P.Toto,B.Diri,Z.Lens,V.Villeret,P.Rucktooa, C.Locht,A.Baulard,B.Deprez
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Key ref:
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N.Willand
et al.
(2010).
Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.
Acs Chem Biol,
5,
1007-1013.
PubMed id:
DOI:
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Date:
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03-Aug-10
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Release date:
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01-Sep-10
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PROCHECK
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Headers
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References
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P9WMC1
(ETHR_MYCTU) -
HTH-type transcriptional regulator EthR from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
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Seq:
Struc:
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216 a.a.
194 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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DOI no:
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Acs Chem Biol
5:1007-1013
(2010)
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PubMed id:
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Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.
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N.Willand,
M.Desroses,
P.Toto,
B.Dirié,
Z.Lens,
V.Villeret,
P.Rucktooa,
C.Locht,
A.Baulard,
B.Deprez.
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ABSTRACT
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Links
