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PDBsum entry 3o2y
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Contents |
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* Residue conservation analysis
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PDB id:
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Isomerase
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Title:
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Structure-function analysis of human l-prostaglandin d synthase bound with fatty acid
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Structure:
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Prostaglandin-h2 d-isomerase. Chain: a, b. Fragment: unp residues 29-190. Synonym: lipocalin-type prostaglandin-d synthase, glutathione- independent pgd synthase, prostaglandin-d2 synthase, pgd2 synthase, pgds2, pgds, beta-trace protein, cerebrin-28. Engineered: yes. Mutation: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.70Å
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R-factor:
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0.200
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R-free:
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0.264
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Authors:
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Y.Zhou,N.Shaw,Y.Li,Y.Zhao,R.Zhang,Z.-J.Liu
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Key ref:
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Y.Zhou
et al.
Structure-Function analysis of human l-Prostaglandin synthase bound with fatty acid.
To be published,
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Date:
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23-Jul-10
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Release date:
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22-Sep-10
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PROCHECK
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Headers
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References
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P41222
(PTGDS_HUMAN) -
Prostaglandin-H2 D-isomerase from Homo sapiens
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Seq:
Struc:
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190 a.a.
160 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class:
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E.C.5.3.99.2
- prostaglandin-D synthase.
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Reaction:
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prostaglandin H2 = prostaglandin D2
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prostaglandin H2
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=
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prostaglandin D2
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Cofactor:
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Glutathione
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Glutathione
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
