PDBsum entry 3nxg

Viral protein

PDB id

3nxg

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Contents

			Protein chains

					259 a.a. *

			Ligands

					GOL ×5


					EDO ×5

			Waters ×987

* Residue conservation analysis

PDB id:

3nxg

Links

Name:

Viral protein

Title:

Jc polyomavirus vp1

Structure:

Major capsid protein vp1. Chain: a, b, c, d, e. Fragment: unp residues 23-290. Synonym: major structural protein vp1. Engineered: yes

Source:

Jc polyomavirus. Jcpyv. Organism_taxid: 10632. Strain: mad-1. Gene: vp1. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.95Å

R-factor:

0.175

R-free:

0.207

Authors:

U.Neu,L.J.Stroeh,T.Stehle

Key ref:

U.Neu et al. (2010). Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif. Cell Host Microbe, 8, 309-319. PubMed id: 20951965

Date:

13-Jul-10

Release date:

17-Nov-10

PROCHECK

	Headers

	References

Protein chains

P03089 (VP1_POVJC) - Major capsid protein VP1 from JC polyomavirus

Seq: Struc:					354 a.a. 259 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.?

[IntEnz] [ExPASy] [KEGG] [BRENDA]

	Cell Host Microbe 8:309-319 (2010)
PubMed id: 20951965

Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif.
U.Neu, M.S.Maginnis, A.S.Palma, L.J.Ströh, C.D.Nelson, T.Feizi, W.J.Atwood, T.Stehle.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

22504179

L.Hu, S.E.Crawford, R.Czako, N.W.Cortes-Penfield, D.F.Smith, J.Le Pendu, M.K.Estes, and B.V.Prasad (2012).
Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen.

Nature, 485, 256-259.

PDB codes:

4drr 4drv 4ds0

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.