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PDBsum entry 3nnh

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protein dna_rna Protein-protein interface(s) links
RNA binding protein/RNA PDB id
3nnh

 

 

 

 

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Contents
Protein chains
86 a.a. *
DNA/RNA
Waters ×29
* Residue conservation analysis
PDB id:
3nnh
Name: RNA binding protein/RNA
Title: Crystal structure of the cugbp1 rrm1 with guuguuuuguuu RNA
Structure: Cugbp elav-like family member 1. Chain: a, c, b, d. Fragment: rrm1 domain (unp residues 14-100). Synonym: celf-1, cug-bp- and etr-3-like factor 1, bruno-like protein 2, RNA-binding protein brunol-2, cug triplet repeat RNA-binding protein 1, cug-bp1, deadenylation factor cug-bp, 50 kda nuclear polyadenylated RNA-binding protein, embryo deadenylation element- binding protein homolog, eden-bp homolog. Engineered: yes.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brunol2, celf1, cugbp, cugbp1, nab50. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
Resolution:
2.75Å     R-factor:   0.191     R-free:   0.263
Authors: M.Teplova,J.Song,H.Gaw,A.Teplov,D.J.Patel
Key ref: M.Teplova et al. (2010). Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1. Structure, 18, 1364-1377. PubMed id: 20947024
Date:
23-Jun-10     Release date:   27-Oct-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q92879  (CELF1_HUMAN) -  CUGBP Elav-like family member 1 from Homo sapiens
Seq:
Struc:
486 a.a.
86 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

DNA/RNA chains
  U-U-G-U-U-U-U-G-U-U-U 11 bases
  G-U-U-G-U-U-U-U-G-U-U 11 bases

 

 
Structure 18:1364-1377 (2010)
PubMed id: 20947024  
 
 
Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1.
M.Teplova, J.Song, H.Y.Gaw, A.Teplov, D.J.Patel.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
21295486 Q.Yang, M.Coseno, G.M.Gilmartin, and S.Doublié (2011).
Crystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA looping.
  Structure, 19, 368-377.
PDB codes: 3q2s 3q2t
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.

 

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