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PDBsum entry 3n4r

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protein ligands Protein-protein interface(s) links
Replication PDB id
3n4r

 

 

 

 

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Contents
Protein chains
93 a.a. *
98 a.a. *
98 a.a. *
93 a.a. *
Ligands
1PE ×4
MLI ×3
Waters ×79
* Residue conservation analysis
PDB id:
3n4r
Name: Replication
Title: Structure of csm1 c-terminal domain, r3 form
Structure: Monopolin complex subunit csm1. Chain: a, b, c, d. Fragment: c-terminal domain (residues 69-181). Synonym: chromosome segregation in meiosis protein 1. Engineered: yes. Mutation: yes
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: csm1, spo86, ycr086w, ycr86w. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.60Å     R-factor:   0.222     R-free:   0.243
Authors: K.D.Corbett,S.C.Harrison
Key ref: K.D.Corbett et al. (2010). The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell, 142, 556-567. PubMed id: 20723757
Date:
22-May-10     Release date:   01-Sep-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P25651  (CSM1_YEAST) -  Monopolin complex subunit CSM1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
190 a.a.
93 a.a.*
Protein chain
Pfam   ArchSchema ?
P25651  (CSM1_YEAST) -  Monopolin complex subunit CSM1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
190 a.a.
98 a.a.*
Protein chain
Pfam   ArchSchema ?
P25651  (CSM1_YEAST) -  Monopolin complex subunit CSM1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
190 a.a.
98 a.a.*
Protein chain
Pfam   ArchSchema ?
P25651  (CSM1_YEAST) -  Monopolin complex subunit CSM1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc:
190 a.a.
93 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 6 residue positions (black crosses)

 

 
Cell 142:556-567 (2010)
PubMed id: 20723757  
 
 
The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments.
K.D.Corbett, C.K.Yip, L.S.Ee, T.Walz, A.Amon, S.C.Harrison.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
22269907 D.J.Gordon, B.Resio, and D.Pellman (2012).
Causes and consequences of aneuploidy in cancer.
  Nat Rev Genet, 13, 189-203.  
22588367 Y.Watanabe (2012).
Geometry and force behind kinetochore orientation: lessons from meiosis.
  Nat Rev Mol Cell Biol, 13, 370-382.  
21633354 K.Tada, H.Susumu, T.Sakuno, and Y.Watanabe (2011).
Condensin association with histone H2A shapes mitotic chromosomes.
  Nature, 474, 477-483.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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