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PDBsum entry 3ldc
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protein metals links
Transport protein PDB id
3ldc

 

 

 

 

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Contents
Protein chain
82 a.a. *
Metals
__K ×5
Waters ×52
* Residue conservation analysis
PDB id:
3ldc
Name: Transport protein
Title: High resolution open mthk pore structure crystallized in 100 mm k+
Structure: Calcium-gated potassium channel mthk. Chain: a. Fragment: mthk k+ channel, residues 28-99. Engineered: yes. Mutation: yes
Source: Methanothermobacter thermautotrophicus. Organism_taxid: 187420. Gene: mthk, mth_1520. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.45Å     R-factor:   0.188     R-free:   0.202
Authors: S.Ye
Key ref: S.Ye et al. (2010). Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore. Nat Struct Biol, 17, 1019-1023. PubMed id: 20676101
Date:
12-Jan-10     Release date:   11-Aug-10    
PROCHECK
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 Headers
 References

Protein chain
O27564  (MTHK_METTH) -  Calcium-gated potassium channel MthK from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Seq:
Struc: 		336 a.a.
82 a.a.*
Key:    Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 

 
Nat Struct Biol 17:1019-1023 (2010)
PubMed id: 20676101  
 
 
Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore.
S.Ye, Y.Li, Y.Jiang.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23262489 D.J.Posson, J.G.McCoy, and C.M.Nimigean (2013).
The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.
  Nat Struct Mol Biol, 20, 159-166.
PDB codes: 4hyo 4hz3
  21518828 A.Alam, and Y.Jiang (2011).
Structural studies of ion selectivity in tetrameric cation channels.
  J Gen Physiol, 137, 397-403.  
  21518830 B.Roux, S.Bernèche, B.Egwolf, B.Lev, S.Y.Noskov, C.N.Rowley, and H.Yu (2011).
Ion selectivity in channels and transporters.
  J Gen Physiol, 137, 415-426.  
21187421 M.G.Derebe, D.B.Sauer, W.Zeng, A.Alam, N.Shi, and Y.Jiang (2011).
Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
  Proc Natl Acad Sci U S A, 108, 598-602.
PDB codes: 3k03 3ouf 3ous
21402935 W.W.Cheng, J.G.McCoy, A.N.Thompson, C.G.Nichols, and C.M.Nimigean (2011).
Mechanism for selectivity-inactivation coupling in KcsA potassium channels.
  Proc Natl Acad Sci U S A, 108, 5272-5277.
PDB code: 3ogc
  20937694 A.S.Thomson, and B.S.Rothberg (2010).
Voltage-dependent inactivation gating at the selectivity filter of the MthK K+ channel.
  J Gen Physiol, 136, 569-579.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.

 

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