PDBsum entry 3h0x

Chaperone

PDB id: 3h0x

Contents

Protein chain

150 a.a. *

Waters ×120

* Residue conservation analysis

PDB id:

3h0x

Name:

Chaperone

Title:

Crystal structure of peptide-binding domain of kar2 protein from saccharomyces cerevisiae

Structure:

78 kda glucose-regulated protein homolog. Chain: a. Fragment: peptide-binding domain: unp residues 438-586. Synonym: grp 78, immunoglobulin heavy chain-binding protein homolog, bip. Engineered: yes

Source:

Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: grp78, j1248, kar2, ssd1, yjl034w. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.92Å R-factor: 0.188 R-free: 0.230

Authors:

J.Osipiuk,L.Bigelow,M.Gu,C.Sahi,E.A.Craig,A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)

Key ref:

J.Osipiuk et al. X-Ray crystal structure of peptide-Binding domain of protein from saccharomyces cerevisiae.. To be published, .

Date:

10-Apr-09 Release date: 21-Apr-09

Protein chain

P16474  (BIP_YEAST) -  Endoplasmic reticulum chaperone BiP from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Seq: 682 a.a.

Struc: 150 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.6.4.10 - non-chaperonin molecular chaperone ATPase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site