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PDBsum entry 3fxt

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protein ligands Protein-protein interface(s) links
Gene regulation PDB id
3fxt

 

 

 

 

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Contents
Protein chain
(+ 2 more) 90 a.a. *
Ligands
GOL ×6
Waters ×354
* Residue conservation analysis
PDB id:
3fxt
Name: Gene regulation
Title: Crystal structure of the n-terminal domain of human nudt6
Structure: Nucleoside diphosphate-linked moiety x motif 6. Chain: a, b, c, d, e, f, g, h. Fragment: n-terminal domain, unp residues 45-134. Synonym: nudix motif 6, protein gfg, gfg-1, antisense basic fibroblast growth factor. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fgf2as, nudt6. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.30Å     R-factor:   0.203     R-free:   0.235
Authors: L.Tresaugues,M.Welin,C.H.Arrowsmith,H.Berglund,C.Bountra,R.Collins, L.G.Dahlgren,A.M.Edwards,S.Flodin,A.Flores,S.Graslund,M.Hammarstrom, A.Johansson,I.Johansson,T.Karlberg,T.Kotenyova,L.Lehtio,M.Moche, M.E.Nilsson,T.Nyman,C.Persson,J.Sagemark,H.Schueler,M.I.Siponen, A.G.Thorsell,S.Van Den Berg,J.Weigelt,M.Wikstrom,P.Nordlund, Structural Genomics Consortium (Sgc)
Key ref: L.Tresaugues et al. Crystal structure of the n-Terminal domain of human nudt6. To be published, .
Date:
21-Jan-09     Release date:   03-Mar-09    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P53370  (NUDT6_HUMAN) -  Nucleoside diphosphate-linked moiety X motif 6 from Homo sapiens
Seq:
Struc:
316 a.a.
90 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.6.1.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

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