PDBsum entry 3fpk

Flavoprotein, oxidoreductase

PDB id: 3fpk

Contents

Protein chains

247 a.a. *

Ligands

FAD ×2

Metals

_MG ×2

_CA

Waters ×711

* Residue conservation analysis

PDB id:

3fpk

Name:

Flavoprotein, oxidoreductase

Title:

Crystal structure of ferredoxin-NADP reductase from salmonella typhimurium

Structure:

Ferredoxin-NADP reductase. Chain: a, b. Engineered: yes

Source:

Salmonella typhimurium. Organism_taxid: 99287. Strain: lt2. Gene: fpr, stm4084. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.70Å R-factor: 0.178 R-free: 0.223

Authors:

Y.Kim,M.Gu,J.Stam,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

Key ref:

Y.Kim et al. Crystal structure of ferredoxin-Nadp reductase from salmonella typhimurium. To be published, .

Date:

05-Jan-09 Release date: 03-Feb-09

Protein chains

Q8ZKP5  (Q8ZKP5_SALTY) -  Flavodoxin/ferredoxin--NADP reductase from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Seq: 248 a.a.

Struc: 247 a.a.

Enzyme reactions

• Enzyme class 2: E.C.1.18.1.2 - ferredoxin--NADP(+) reductase.
• Pathway: Methionine Synthase
• Reaction: 2 reduced [2Fe-2S]-[ferredoxin] + NADP⁺ + H⁺ = 2 oxidized [2Fe-2S]- [ferredoxin] + NADPH
• Cofactor: FAD

FAD (Bound ligand (Het Group name = FAD) corresponds exactly)

• Enzyme class 3: E.C.1.19.1.1 - flavodoxin--NADP(+) reductase.
• Reaction: reduced [flavodoxin] + NADP⁺ = oxidized [flavodoxin] + NADPH + 2 H⁺
• Cofactor: FAD

FAD (Bound ligand (Het Group name = FAD) corresponds exactly)

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site