PDBsum entry 3eeg

Transferase

PDB id: 3eeg

Contents

Protein chains

267 a.a. *

Waters ×56

* Residue conservation analysis

PDB id:

3eeg

Name:

Transferase

Title:

Crystal structure of a 2-isopropylmalate synthase from cytophaga hutchinsonii

Structure:

2-isopropylmalate synthase. Chain: a, b. Engineered: yes

Source:

Cytophaga hutchinsonii atcc 33406. Organism_taxid: 269798. Gene: leua, chu_3741. Expressed in: escherichia coli.

Resolution:

2.78Å R-factor: 0.245 R-free: 0.298

Authors:

R.Sugadev,S.K.Burley,S.Swaminathan,New York Sgx Research Center For Structural Genomics (Nysgxrc)

Key ref:

R.Sugadev et al. Crystal structure of a 2-Isopropylmalate synthase from cytophaga hutchinsonii. To be published, .

Date:

04-Sep-08 Release date: 16-Sep-08

Protein chains

Q11NN9  (Q11NN9_CYTH3) -

Enzyme reactions

• Enzyme class: E.C.2.3.3.13 - 2-isopropylmalate synthase.
• Pathway: Leucine Biosynthesis
• Reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H⁺
• Cofactor: K(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site