PDBsum entry 3c4j

Hydrolase

PDB id: 3c4j

Contents

Protein chains

242 a.a. *

Ligands

AGS ×2

Metals

_MG ×2

Waters ×228

* Residue conservation analysis

PDB id:

3c4j

Name:

Hydrolase

Title:

Abc protein artp in complex with atp-gamma-s

Structure:

Amino acid abc transporter (artp). Chain: a, b. Engineered: yes

Source:

Geobacillus stearothermophilus. Organism_taxid: 1422. Strain: dsmz 13240. Gene: artp. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.33Å R-factor: 0.224 R-free: 0.276

Authors:

P.F.Thaben,V.Eckey,F.Scheffel,W.Saenger,E.Schneider,A.Vahedi-Faridi

Key ref:

P.F.Thaben et al. Crystal structures of the ATP-Binding cassette (abc) protein artp from geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region. To be published, .

Date:

30-Jan-08 Release date: 03-Feb-09

Protein chains

D0VWX4  (D0VWX4_GEOSE) -  Amino acid ABC transporter from Geobacillus stearothermophilus

Seq: 243 a.a.

Struc: 242 a.a.

Enzyme reactions

• Enzyme class: E.C.3.6.3.21 - Transferred entry: 7.4.2.1.
• Reaction: ATP + H₂O + polar amino acid(Out) = ADP + phosphate + polar amino acid(In)

ATP + H(2)O + polar amino acid(Out) = ADP (Bound ligand (Het Group name = AGS) matches with 87.10% similarity) + phosphate + polar amino acid(In)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site