PDBsum entry 3bme

Oxidoreductase

PDB id: 3bme

Contents

Protein chains

249 a.a. *

Ligands

NAP ×4

DX2 ×4

ACT ×2

DTT

Waters ×611

* Residue conservation analysis

Obsolete entry

PDB id:

3bme

Name:

Oxidoreductase

Title:

Structure of pteridine reductase 1 (ptr1) from trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor (compound dx2)

Structure:

Pteridine reductase. Chain: a, c, d. Engineered: yes. Pteridine reductase. Chain: b. Engineered: yes

Source:

Trypanosoma brucei brucei. Organism_taxid: 5702. Gene: ptr1. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.80Å R-factor: 0.154 R-free: 0.191

Authors:

L.B.Tulloch,W.N.Hunter

Key ref:

L.B.Tulloch and w.n.hunter Structure of pteridine reductase 1 (ptr1) from trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitors. To be published, .

Date:

13-Dec-07 Release date: 16-Dec-08

Protein chains

O76290  (O76290_TRYBB) -  Pteridine reductase from Trypanosoma brucei brucei

Seq: 268 a.a.

Struc: 249 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)