PDBsum entry 3b1d

Lyase

PDB id

3b1d

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Contents

			Protein chains

					387 a.a.

			Ligands

					PLP-PLS ×2


					EPE ×11


					PLS ×2

			Metals

					_NA ×4

			Waters ×1616

PDB id:

3b1d

Links

Name:

Lyase

Title:

Crystal structure of betac-s lyase from streptococcus anginosus in complex with l-serine: external aldimine form

Structure:

Betac-s lyase. Chain: a, b, c, d. Engineered: yes

Source:

Streptococcus anginosus. Organism_taxid: 1328. Strain: imu102. Gene: lcd. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.66Å

R-factor:

0.152

R-free:

0.177

Authors:

Y.Kezuka,Y.Yoshida,T.Nonaka

Key ref:

Y.Kezuka et al. (2012). Structural insights into catalysis by βC-S lyase from Streptococcus anginosus. Proteins, 80, 2447-2458. PubMed id: 22674431

Date:

29-Jun-11

Release date:

27-Jun-12

PROCHECK

	Headers

	References

Protein chains

A6BMJ3 (A6BMJ3_STRAP) - cysteine-S-conjugate beta-lyase from Streptococcus anginosus

Seq: Struc:					388 a.a. 387 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.4.4.1.13 - cysteine-S-conjugate beta-lyase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4⁺

S-substituted L-cysteine	+	H2O	=	thiol	+	pyruvate	+	NH4(+)

Cofactor:

Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate
Bound ligand (Het Group name = PLP) matches with 93.75% similarity

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

	Proteins 80:2447-2458 (2012)
PubMed id: 22674431

Structural insights into catalysis by βC-S lyase from Streptococcus anginosus.
Y.Kezuka, Y.Yoshida, T.Nonaka.

ABSTRACT

No abstract given.