PDBsum entry 3al2

DNA binding protein, protein binding

PDB id: 3al2

Contents

Protein chain

220 a.a. *

Ligands

SO4 ×2

Waters ×182

* Residue conservation analysis

PDB id:

3al2

Name:

DNA binding protein, protein binding

Title:

Crystal structure of topbp1 brct7/8

Structure:

DNA topoisomerase 2-binding protein 1. Chain: a. Fragment: brct7 and brct8, unp residues 1264-1493. Synonym: DNA topoisomerase ii-binding protein 1, DNA topoisomerase ii-beta-binding protein 1, topbp1. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0259, topbp1. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.00Å R-factor: 0.172 R-free: 0.204

Authors:

C.C.Leung,J.N.Glover

Key ref:

C.C.Leung et al. (2011). Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control. J Biol Chem, 286, 4292-4301. PubMed id: 21127055

Date:

22-Jul-10 Release date: 01-Dec-10

Protein chain

Q92547  (TOPB1_HUMAN) -  DNA topoisomerase 2-binding protein 1 from Homo sapiens

Seq: 1522 a.a.

Struc: 220 a.a.

J Biol Chem 286:4292-4301 (2011)

PubMed id: 21127055

Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.

C.C.Leung, Z.Gong, J.Chen, J.N.Glover.

ABSTRACT

No abstract given.