PDBsum entry 3zg9

Penicillin-binding protein

PDB id: 3zg9

Contents

Protein chains

41 a.a.

456 a.a.

Ligands

DXF

GOL ×4

Waters ×221

PDB id:

3zg9

Name:

Penicillin-binding protein

Title:

Crystal structure of penicillin-binding protein 4 from listeria monocytogenes in the cefuroxime bound form

Structure:

Penicillin-binding protein 4. Chain: a. Fragment: residues 73-119. Synonym: lmo2229 protein. Engineered: yes. Other_details: proteolysis from 120-177. Penicillin-binding protein 4. Chain: b. Fragment: residues 178-714.

Source:

Listeria monocytogenes. Organism_taxid: 1639. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril.

Resolution:

1.80Å R-factor: 0.176 R-free: 0.209

Authors:

J.H.Jeong,Y.G.Kim

Key ref:

J.H.Jeong and y.g.kim Crystal structures of penicillin-Binding protein 4 fr listeria monocytogenes. To be published, .

Date:

17-Dec-12 Release date: 15-Jan-14

Protein chain

Q8Y547  (Q8Y547_LISMO) -  peptidoglycan glycosyltransferase from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

Seq: 714 a.a.

Struc: 41 a.a.

Protein chain

Q8Y547  (Q8Y547_LISMO) -  peptidoglycan glycosyltransferase from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

Seq: 714 a.a.

Struc: 456 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.2.4.99.28 - peptidoglycan glycosyltransferase.
• Reaction: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)- di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)- Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa- cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D- Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans,octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site