PDBsum entry 3vvb

Lyase

PDB id: 3vvb

Contents

Protein chain

270 a.a.

Ligands

NAP

Waters ×3

PDB id:

3vvb

Name:

Lyase

Title:

Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in apo form

Structure:

Cape. Chain: a. Engineered: yes

Source:

Staphylococcus aureus. Organism_taxid: 158878. Strain: mu50. Gene: cape. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.80Å R-factor: 0.238 R-free: 0.276

Authors:

T.Miyafusa,J.M.Caaveiro,Y.Tanaka,K.Tsumoto

Key ref:

T.Miyafusa et al. Crystal structure of the capsular polysaccharide synthesizing protein cape of staphylococcus aureus.. Biosci rep, . PubMed id: 23611437

Date:

18-Jul-12 Release date: 12-Jun-13

Protein chain

A0A0H3JPH0  (A0A0H3JPH0_STAAM) -  Galactowaldenase from Staphylococcus aureus (strain Mu50 / ATCC 700699)

Seq: 342 a.a.

Struc: 270 a.a.

Enzyme reactions

• Enzyme class: E.C.4.2.1.115 - UDP-N-acetylglucosamine 4,6-dehydratase (inverting).
• Reaction: UDP-N-acetyl-alpha-D-glucosamine = UDP-2-acetamido-2,6-dideoxy-beta-L- arabino-hex-4-ulose + H2O
• Cofactor: NADPH

NADPH (Bound ligand (Het Group name = NAP) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site