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PDBsum entry 3vu8
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protein ligands metals links
Ligase PDB id
3vu8

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
500 a.a.
Ligands
MDS
Metals
_ZN
Waters ×157
PDB id:
3vu8
Name: Ligase
Title: Metionyl-tRNA synthetase from thermus thermophilus complexed with methionyl-adenylate analogue
Structure: Methionine--tRNA ligase. Chain: a. Fragment: unp residues 1-502. Synonym: methionyl-tRNA synthetase, metrs. Engineered: yes
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Gene: mets. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.20Å     R-factor:   0.200     R-free:   0.300
Authors: M.Konno,M.Kato-Murayama,S.Toma-Fukai,E.Uchikawa,O.Nureki,S.Yokoyama
Key ref: M.Konno et al. The modeling of structures of specific conformation o homosysteine-Amp leading to thiolactone-Formation on ia aminoacyl-Trna synthetases. To be published, .
Date:
22-Jun-12     Release date:   26-Jun-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P23395  (SYM_THET8) -  Methionine--tRNA ligase from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Seq:
Struc: 		 
Seq:
Struc: 		618 a.a.
500 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.1.1.10  - methionine--tRNA ligase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate
tRNA(Met)
 +
L-methionine
Bound ligand (Het Group name = MDS)
matches with 72.73% similarity 		+ ATP
 = L-methionyl-tRNA(Met)
 + AMP
 + diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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