PDBsum entry 3vll

Oxidoreductase/oxidoreductase inhibitor

PDB id: 3vll

Contents

Protein chains

703 a.a.

Ligands

HEM ×2

SHA ×2

Waters ×242

PDB id:

3vll

Name:

Oxidoreductase/oxidoreductase inhibitor

Title:

Crystal structure analysis of the ser305ala variant of katg from haloarcula marismortui complexes with inhibitor sha

Structure:

Catalase-peroxidase 2. Chain: a, b. Synonym: katg, cp 2, peroxidase/catalase 2. Engineered: yes. Mutation: yes

Source:

Haloarcula marismortui. Organism_taxid: 272569. Strain: atcc 43049. Gene: katg2. Expressed in: haloferax volcanii. Expression_system_taxid: 2246

Resolution:

2.00Å R-factor: 0.247 R-free: 0.271

Authors:

T.Sato,W.Higuchi,K.Yoshimatsu,T.Fujiwara

Key ref:

T.Sato et al. Crystal structure and kinetics studies on ser305ala V of katg from haloarcula marismortui and its complexes inhibitor sha. To be published, .

Date:

01-Dec-11 Release date: 05-Dec-12

Protein chains

O59651  (KATG2_HALMA) -  Catalase-peroxidase 2 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 731 a.a.

Struc: 703 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.1.11.1.21 - catalase peroxidase.
• Reaction:
  1. H2O2 + AH2 = A + 2 H2O
  2. 2 H2O2 = O2 + 2 H2O

Molecule diagrams generated from .mol files obtained from the KEGG ftp site