PDBsum entry 3vj6

Immune system

PDB id: 3vj6

Contents

Protein chains

277 a.a.

100 a.a.

Ligands

ALA-MET-ALA-PRO-ARG-THR-LEU-LEU-LEU

Metals

_NI ×4

Waters ×263

PDB id:

3vj6

Name:

Immune system

Title:

Structure of the mhc class ib molecule qa-1b

Structure:

H-2 class i histocompatibility antigen, d-37 alpha chain. Chain: a. Fragment: qa-1b extracellular domain, unp residues 21-297. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. Qdm peptide. Chain: p.

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: h2-t23. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: b2m. Synthetic: yes. Other_details: synthesised peptide from mhc-classia leader sequence

Resolution:

1.90Å R-factor: 0.203 R-free: 0.242

Authors:

L.Zeng,C.S.Clements,J.Rossjohn

Key ref:

L.Zeng et al. (2012). A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b. J Immunol, 188, 302-310. PubMed id: 22131332

Date:

12-Oct-11 Release date: 14-Mar-12

Protein chain

P06339  (HA15_MOUSE) -  H-2 class I histocompatibility antigen, D-37 alpha chain from Mus musculus

Seq: 357 a.a.

Struc: 277 a.a.

Protein chain

P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

J Immunol 188:302-310 (2012)

PubMed id: 22131332

A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b.

L.Zeng, L.C.Sullivan, J.P.Vivian, N.G.Walpole, C.M.Harpur, J.Rossjohn, C.S.Clements, A.G.Brooks.

ABSTRACT

No abstract given.